My wife and I have stayed at either The Venetian or Palazzo for the last 4 trips to Las Vegas, and we will return to Venetian again in two months. This is probably the classiest hotel on the strip and the player's club is absolutely fantastic. We are not high rollers, but we constanly get 4 free nights each year. Last year, they even comped us an additional night just for charging our breakfasts and dinners to our room. The video poker bars are also a great bonus because they give you top shelf drinks for free with only $20 in the poker machine. We love the shops, the canals, the restaurants, and especially the magnificent suits at The Venetian or Palazzo. BRAVO !!
My wife and I have stayed at the Venetian about once a year since 2002. If you're looking for a "cheap Vegas deal" this probably isn't the place for you (though we get email and snail mail offers for reduced room rates all the time after signing up for their player's club): they're aiming for the same crowd as Wynn and Bellagio. And they do it well.
Unlike other posters here our customer service experiences have been exceptional: we're not "high rollers" by any stretch but the staff has been almost uniformally friendly and helpful. The rooms are huge, well-maintained, comfortable.
There is a good selection of slots (though the number of them were reduced somewhat a couple years ago when they used some slot space to build their poker room) of all denominations (even nickels: look around the staircase beneath the streetside Canal Shoppes entrance). Table minimums have dropped to the $10 level most the time. The casino has never been "smelly" and I've played BJ next to a smoker for half the night without a problem.